P-NITROPHENYL PHENYL SULFONE
4-Nitrodiphenyl Sulfone
CAS: 1146-39-0
Molecular Formula: C12H9NO4S
P-NITROPHENYL PHENYL SULFONE - Names and Identifiers
| Name | 4-Nitrodiphenyl Sulfone |
| Synonyms | TIMTEC-BB SBB008080 4-Nitrodiphenyl Sulfone 4-NITRODIPHENYL SULFONE 4-NITRODIPHENYL SULPHONE P-NITROPHENYL PHENYL SULFONE p-Nitrophenyl Phenyl Sulfone 4-Nitrophenyl phenyl sulfone 1-NITRO-4-(PHENYLSULFONYL)BENZENE 1-Nitro-4-(phenylsulfonyl)benzene Benzene, 1-nitro-4-(phenylsulfonyl)- 4-Nitrophenylsulphonylbenzene~Phenyl 4-nitrophenyl sulphone |
| CAS | 1146-39-0 |
| InChI | InChI=1/C12H9NO4S/c14-13(15)10-6-8-12(9-7-10)18(16,17)11-4-2-1-3-5-11/h1-9H |
P-NITROPHENYL PHENYL SULFONE - Physico-chemical Properties
| Molecular Formula | C12H9NO4S |
| Molar Mass | 263.27 |
| Density | 1.388g/cm3 |
| Melting Point | 141-142°C |
| Boling Point | 461.5°C at 760 mmHg |
| Flash Point | 232.9°C |
| Vapor Presure | 2.93E-08mmHg at 25°C |
| BRN | 2055217 |
| Storage Condition | 2-8°C |
| Refractive Index | 1.616 |
| MDL | MFCD00043616 |
P-NITROPHENYL PHENYL SULFONE - Risk and Safety
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
P-NITROPHENYL PHENYL SULFONE - Introduction
4-Nitrobiphenyl sulfone, also known as DNPP(4-Nitrodiphenylsulfone), is an organic compound. The following is a description of the properties, uses, preparation and safety information of 4-nitrobiphenyl sulfone:
Nature:
-Appearance: White crystalline solid
-Molecular formula: C12H9NO5S
-Molecular weight: 275.27g/mol
-Melting point: 174-176°C
-not soluble in water, soluble in organic solvents such as ethanol and ether
Use:
-4-Nitrobiphenyl sulfone is mainly used as an important organic synthesis intermediate.
-In the field of drug development, it can be used to synthesize antibiotics, anti-cancer drugs, non-steroidal anti-inflammatory drugs, etc.
-In addition, it can also be used to synthesize dyes, plastics and polymers.
Method:
The preparation of-4-nitrobiphenyl sulfone can be obtained by nitration of 4-chlorobiphenyl sulfone. First, 4-chlorobiphenyl sulfone is reacted with concentrated nitric acid, nitrated at an appropriate temperature and reaction time, then washed with dilute alkali solution, crystallized and dried to obtain the product.
Safety Information:
-4-Nitrobiphenyl sulfone needs to pay attention to safety precautions during operation to avoid inhalation, contact with skin and ingestion.
-It is irritating and may cause damage to the eyes, skin and respiratory tract, so personal protective equipment such as protective glasses, gloves and protective face masks should be worn during operation.
-During storage and transportation, contact with incompatible substances such as combustibles and oxidants should be avoided.
-When using 4-nitrobiphenyl sulfone in the laboratory, follow the relevant chemical safety practices and dispose of the waste in the correct way.
Nature:
-Appearance: White crystalline solid
-Molecular formula: C12H9NO5S
-Molecular weight: 275.27g/mol
-Melting point: 174-176°C
-not soluble in water, soluble in organic solvents such as ethanol and ether
Use:
-4-Nitrobiphenyl sulfone is mainly used as an important organic synthesis intermediate.
-In the field of drug development, it can be used to synthesize antibiotics, anti-cancer drugs, non-steroidal anti-inflammatory drugs, etc.
-In addition, it can also be used to synthesize dyes, plastics and polymers.
Method:
The preparation of-4-nitrobiphenyl sulfone can be obtained by nitration of 4-chlorobiphenyl sulfone. First, 4-chlorobiphenyl sulfone is reacted with concentrated nitric acid, nitrated at an appropriate temperature and reaction time, then washed with dilute alkali solution, crystallized and dried to obtain the product.
Safety Information:
-4-Nitrobiphenyl sulfone needs to pay attention to safety precautions during operation to avoid inhalation, contact with skin and ingestion.
-It is irritating and may cause damage to the eyes, skin and respiratory tract, so personal protective equipment such as protective glasses, gloves and protective face masks should be worn during operation.
-During storage and transportation, contact with incompatible substances such as combustibles and oxidants should be avoided.
-When using 4-nitrobiphenyl sulfone in the laboratory, follow the relevant chemical safety practices and dispose of the waste in the correct way.
Last Update：2024-04-09 21:01:54
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